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Delta Variant of SARS-CoV-2 on 6/18/21

SARS-CoV-2 Delta variant, also known as lineage B.1.617.2, and commonly referred to as the Indian variant[a] is a variant of lineage B.1.617 of SARS-CoV-2, the virus that causes COVID-19.[2] It was first detected in India in late 2020.[3][4] The WHO named it the Delta variant on 31 May 2021.[5]

It has mutations in the gene encoding the SARS-CoV-2 spike protein[6] causing the substitutions T478K, P681R and L452R,[7] which are known to affect transmissibility of the virus as well as whether it can be neutralised by antibodies for the original "wild type" COVID-19 virus.[8] Public Health England (PHE) in May 2020 observed secondary attack rates to be 51-67% higher than the alpha variant.[9]

On 7 May 2021, Public Health England changed their classification of lineage B.1.617.2 from a variant under investigation (VUI) to a variant of concern (VOC) based on an assessment of transmissibility being at least equivalent to B.1.1.7 (Alpha variant), first identified in the UK (Kent).[10] Subsequently on 11 May 2021, the World Health Organization (WHO) also classified this lineage VOC, and said that it showed evidence of higher transmissibility and reduced neutralisation. The variant is thought to be partly responsible for India's second wave of the pandemic beginning in February 2021.[11][12][13]


Contents
Classification[edit]

The Delta variant has mutations in the gene encoding the SARS-CoV-2 spike protein[6] causing the substitutions E484Q and L452R.[8] It is identified as the 21A clade under the Nextstrain phylogenetic classification system.[14]

At the end of May 2021, the WHO assigned the label Delta to lineage B.1.617.2 after introducing a new policy of using Greek letters for variants of concern and variants of interest.[5]
Mutations[edit]
Defining mutations in the
SARS-CoV-2 Delta variant
show


The B.1.617.2 genome has 13 mutations (15 or 17 according to some sources,[which?] depending on whether more common mutations are included) which produce alterations in the amino-acid sequences of the proteins it encodes.[4] Four of them, all of which are in the virus's spike protein code, are of concern:
D614G. The substitution at position 614, an aspartic acid-to-glycine substitution, is shared with other highly transmissible variants like Alpha, Beta and Gamma.[16]
T478K.[16][17] The exchange at position 478 is a threonine-to-lysine substitution.[18]
L452R. The substitution at position 452, a leucine-to-arginine substitution, confers stronger affinity of the spike protein for the ACE2 receptor and decreased recognition capability of the immune system.[8][19] These mutations, when taken individually, are not unique to the variant; rather, their simultaneous occurrence is.[8][20]
P681R. The substitution at position 681, a proline-to-arginine substitution, which, according to William A. Haseltine, may boost cell-level infectivity of the variant "by facilitating cleavage of the S precursor protein to the active S1/S2 configuration".[21]

The E484Q mutation is not present in the B.1.617.2 genome.[21][22]

There are three sublineages of B.1.617 categorised so far.

B.1.617.1 (VUI-21APR-01) was designated a Variant Under Investigation in April 2021 by Public Health England. Later in April 2021, two other variants B.1.617.2 (VUI-21APR-02) and B.1.617.3 (VUI-21APR-03) were designated as Variants Under Investigation. While B.1.617.3 shares the L452R and E484Q mutations found in B.1.617.1, B.1.617.2 lacks the E484Q mutation. B.1.617.2 has the T478K mutation, not found in B.1.617.1 and B.1.617.3.[23][24] Simultaneously, the ECDC released a brief maintaining all three sublineages of B.1.617 as VoI, estimating that a "greater understanding of the risks related to these B.1.617 lineages is needed before any modification of current measures can be considered".[25]
Symptoms[edit]
See also: Symptoms of COVID-19

The most common symptoms may have changed from the most common symptoms previously associated with standard COVID-19. "Headaches, a sore throat and a runny nose are the most common symptoms". (The Guardian) Infected people may mistake the symptoms for a bad cold and not realize they need to isolate. "So, the number one symptom is headache … followed by sore throat, runny nose and fever.” "It might just feel like a bad cold or some funny 'off' feeling - but do stay at home and do get a test." (King’s College London professor, Tim Spector)[26][better source needed][27] "In the United Kingdom, where the Delta variant makes up 91 percent of new cases, one study found that the most reported symptoms were headache, sore throat, and runny nose." (US publication Healthline)[28]
Treatment[edit]
See also: Treatment and management of COVID-19

The treatment for those infected by the SARS-CoV-2 Delta variant is as per others infected by COVID-19.
Vaccine efficacy[edit]


This section needs to be updated. The reason given is: This section is contains more RECENTNEWS about the B1.617 variant in general rather than the Delta Variant. This section needs to be concentrating on MEDRS information on WHO supported vaccine efficacy and effectiveness against the Delta variant in particular. The Pfizer-BioNTech vaccine was shown to be 79-88% effective against the Delta variant in U.K studies.. Please update this article to reflect recent events or newly available information. (June 2021)


ICMR found that convalescent sera of the COVID-19 cases and recipients of Bharat Biotech's BBV152 (Covaxin) were able to neutralise VUI B.1.617 although with a lower efficacy.[29]

Anurag Agrawal, the director of the Institute of Genomics and Integrative Biology (IGIB), said the study on the effectiveness of the available vaccines on lineage B.1.617 suggests that post-vaccination, the infections are milder. He tweeted:


Initial positive neutralization studies of B.1.617, with both post-Covaxin or Covishield sera, are correlatable with the milder disease during post-vaccination breakthrough infections. This is positive while we get quantitative data for a better understanding of infection protection.[30]

Anthony Fauci, the Chief Medical Advisor to the President of US, has also expressed his confidence regarding the preliminary results. In an interview on 28 April, he said:


This is something where we're still gaining data daily. But the most recent data was looking at convalescent Sera of COVID-19 cases and people who received the vaccine used in India, the Covaxin. It was found to neutralise the 617 variants.[31]

Another study by the Centre for Cellular and Molecular Biology (CCMB) in Hyderabad found Covishield (Oxford–AstraZeneca) vaccinated sera offers protection against lineage B.1.617. Rakesh Mishra, the Director of CCMB, said in a tweet on 28 April:


Very preliminary but encouraging result: #Covishield protects against #B1617. Early results using in vitro neutralisation assay show that both convalescent (prior infection) sera and Covishield vaccinated sera offer protection against the B.1.617 variant, aka #DoubleMutant.[32]

The WHO has said current vaccines will continue to be effective against the variant. In an update in May, they said there may be some evidence of "reduced neutralization".[33] A study conducted by the Public Health England, has found that both Pfizer-BioNTech and AstraZeneca-Oxford vaccines provide a 33% protection against symptomatic disease caused by the variant after the first dose. Two weeks after the second dose the Pfizer-BioNTech vaccine was found to be 88% effective at stopping symptomatic disease from the Delta variant while the AstraZeneca-Oxford vaccine was 60% effective against the variant.[34][35]

In another laboratory study, a group of scientists led by Olivier Schwartz, at the Pasteur Institute reported a slightly diminished efficacy by Pfizer vaccine and low levels of antibodies induction by AstraZeneca vaccine against the Delta variant.[36][37] A group of researchers from the Francis Crick Institute, published in The Lancet shows that humans fully vaccinated with the Pfizer-BioNTech vaccine are likely to have more than five times lower levels of neutralizing antibodies against the Delta variant.[38][39]

In June 2021, Public Health England announced it had conducted a study which found that after two shots, the Pfizer-BioNTech vaccine and the AstraZeneca vaccine are respectively 96% and 92% effective at preventing hospitalisation from the Delta variant.[40]
Epidemiology[edit]


This section needs to be updated. Please update this article to reflect recent events or newly available information. (June 2021)


Emerging research suggests the variant may be more transmissible than previously evolved ones.[41] Whether the effectiveness of currently-deployed vaccines is affected remains under investigation.[42][43][44]

Surveillance data from the Indian government's Integrated Disease Surveillance Programme (IDSP) shows that around 32% of patients, both hospitalised and outside hospitals, were aged below 30 in the second wave compared to 31% during the first wave, among people aged 30–40 the infection rate stayed at 21%. Hospitalisation in the 20-39 bracket increased to 25.5% from 23.7% while the 0-19 range increased to 5.8% from 4.2%. The data also showed a higher proportion of asymptomatic patients were admitted during the second wave, with more complaints of breathlessness.[45]
Statistics[edit]

By 13 May 2021, more than 4,500 sequences of the variant had been detected in about 60 countries.[3][46] Reported numbers of sequences in countries with detections are:
Cases by country (As of 30 May 2021)
Country/AreaConfirmed Delta variant cases:
(PANGOLIN)[47] as of 16 JuneConfirmed cases
(GISAID)[3] as of 30 MayConfirmed cases
(PANGOLIN)[48] as of 1 JuneCases (other sources)First detection India 4,208 3,364 3,571 5 October 2020
United Kingdom 26,694 8,956 9,273 22 February 2021
United States 2,247 1,539 1,542 23 February 2021
Singapore 244 156 156 26 February 2021
Australia 154 145 144 16 March 2021
Canada 94 163 - 1,539[49] 15 March 2021
Germany 710 420 420 1 March 2021
Fiji - - - 42[50] 28 April 2021
Israel 35 38 35 41[51][52][53] 16 April 2021
Denmark 90 105 105 8 March 2021
Japan 147 174 165 28 March 2021
Bahrain - 19 19 5 April 2021
Poland 69 34 34 16[54] 26 April 2021
Ireland 141 155 155 26 February 2021
Switzerland 83 61 64 29 March 2021
Belgium 220 98 120 25 March 2021
France 104 88 85 21 February 2021
New Zealand - 15 15 9 March 2021
China - 7 7 24 April 2021
Nepal - 7 - 9[55] 28 April 2021
Angola - 8 8 14 January 2021
Hong Kong - 10 8 22 April 2021
Portugal 62 38 52 5 April 2021
Sweden 37 17 17 26 March 2021
Luxembourg 51 7 6 15 April 2021
The Netherlands 75 51 50 6 April 2021
Italy 164 80 81 2 April 2021
South Korea - 6 7 26 March 2021
Spain 182 65 65 22 April 2021
Turkey - 1 - 5[56] 28 April 2021
Finland - 1 - 60[57][58][59] 18 March 2021
Jordan - 5 4 21 April 2021
Russia 163 4 4 16[60] 21 April 2021
Bangladesh 43 20 20 9[61][62] 28 April 2021
Czech Republic - 7 2 24 April 2021
Greece - 2 2 23 March 2021
Guadeloupe - 2 2 10 March 2021
Indonesia 48 32 32 3 April 2021
Argentina - 1 - 2[63] 24 April 2021
Morocco - 1 - 2[64] 3 May 2021
Thailand 92 1 - 2[65] 24 April 2021
Sint Maarten - 4 - 19 March 2021
Algeria - - - 6[66] April 2021
Aruba - 3 3 16 April 2021
Austria - 5 - 17 April 2021
Botswana - 1 - 2[67] 28 April 2021
Cambodia - 1 - 5 April 2021
Curacao - 1 - 23 April 2021
Cyprus - - - 4[68] 19 May 2021
DR Congo - 6 - 5[69] 3 May 2021
Haiti - - - (number unreported)[70]
Iran - 6 6 3[71] 11 May 2021
Kenya - - - 5[69][72] May 2021
Kyrgyzstan - - - (number unreported)[70]
Malaysia - 4 - 10 April 2021
Mexico 32 26 27 5 April 2021
Nigeria - - - 1[69] May 2021
Norway 68 20 20 1[73] 15 April 2021
Panama - - - 1[74] April 2021
Romania - 19 19 26 April 2021
Reunion - 1 - 4 May 2021
Slovenia - 2 - 20 April 2021
South Africa - 14 15 4[75] 30 April 2021
Sri Lanka - 1 - 1[76] 30 April 2021
Uganda - 5 4 1[77] 26 March 2021
Philippines - - - 13[78][79][80] 11 May 2021
Uzbekistan - - - (number unreported)[70]
Vietnam 54 - - 12[81][82] 18 April 2021
Brazil - 2 2 10 [83] [84] 20 May 2021[85] [86] [87]
Qatar - 8 - 19 April 2021
Guam - 1 - 26 April 2021
Ghana - 5 - 20 April 2021
Pakistan - 1 - 16 May 2021
Lithuania - - - 1[88] 17 June 2021
World (73 countries) Total: 36,828
(solely B.1.617.2) Total: 16,049 Total: 16,366
incl. B.1.617.1, B.1.617.2, and B.1.617.3 1,729 Total as of 30 May 2021.


The latest available data from the end of May indicates prevalence in the U.S., the Netherlands and Germany was in the 1 % to 10% range. Surveillance data from the U.S. and the Netherlands indicates the Delta variant is growing by about a factor of 2 every weeks with respect to the Alpha variant, so it is expected to become dominant in around July or August in these countries.[89][90][91][92]
History[edit]

In countries other than India, the first cases of the variant were detected in late February 2021, including the United Kingdom on 22 February, the United States on 23 February and Singapore on 26 February.[48][4][3]

British scientists at Public Health England redesignated the B.1.617.2 variant on 7 May 2021 as "variant of concern" (VOC-21APR-02),[93] after they flagged evidence in May 2021 that it spreads more quickly than the original version of the virus. Another reason was that they identified 48 clusters of B.1.617.2, some of which revealed a degree of community transmission.[94][95] With cases from the Delta variant having risen quickly, British scientists considered the Delta variant having overtaken the Alpha variant as the dominant variant of SARS-CoV-2 in the UK in early June 2021.[96] Researchers at Public Health England later found that over 90% of new cases in the UK in the early part of June 2021 were the Delta variant; they also cited evidence that the Delta variant was associated with an approximately 60% increased risk of household transmission compared to the Alpha variant.[97]

Canada's first confirmed case of the variant was identified in Quebec on 21 April 2021, and later the same day 39 cases of the variant were identified in British Columbia.[98] Alberta reported a single case of the variant on 22 April 2021.[99] Nova Scotia reported two Delta variant cases in June 2021.[100]

Fiji also confirmed its first case of the variant on 19 April 2021 in Lautoka, and has since then climbed up to 42 cases and counting.[101] The variant has been identified as a super-spreader and has led to the lockdowns of five cities (Lautoka, Nadi, Suva, Lami and Nausori), an area which accounts for almost two-thirds of the country's population.

On 29 April 2021, health officials from Finland's the Ministry of Social Affairs and Health (STM) and the Finnish Institute for Health and Welfare (THL) reported that the variant had been detected in three samples dating back to March 2021.[57]

The Philippines confirmed its first two cases of the variant on 11 May 2021, despite the imposed travel ban of the country from the nations in the Indian subcontinent (except for Bhutan and Maldives). Both patients have no travel history from India for the past 14 days, but instead from Oman and UAE.[102]

North Macedonia confirmed its first case of the variant on 7 June 2021 after a person who was recovering from the virus in Iraq was transported to North Macedonia. In a laboratory test, the variant was detected in the person.[citation needed]

The detection of B.1.617 was hampered in some countries by a lack of specialised kits for the variant and laboratories that can perform the genetic test.[103][104] For example, as of 18 May, Pakistan had not reported any cases, but authorities noted that 15% of COVID-19 samples in the country were of an "unknown variant"; they could not say if it was B.1.617 because they were unable to test for it. Other countries had reported travellers arriving from Pakistan that were infected with B.1.617.[103]

Society and culture[edit]
International reactions[edit]

After the rise in cases from the second wave, at least 20 countries imposed travel bans and restrictions on passengers from India in April and May. UK prime minister Boris Johnson cancelled his visit to India twice, while Japanese Prime Minister Yoshihide Suga postponed his April trip.[105][106][107]

In May 2021, residents of two tower blocks in Velbert, Germany were quarantined after a woman in the building tested positive for the variant.[108]

In May, Delhi Chief Minister Arvind Kejriwal said that a new coronavirus variant from Singapore was extremely dangerous for children and could result in a third wave in India. Singapore's Ministry of Health said there was no Singapore variant nor any evidence of a coronavirus variant extremely dangerous for children,[109][110] and that the increase in COVID-19 cases came from the Delta variant.[110]

On 14 June, the British prime minister Boris Johnson announced that the proposed end of all restrictions on "Freedom Day" (21 June) in the United Kingdom was delayed for up to 4 weeks and vaccination roll-out was accelerated following concerns over the Delta variant, which accounted for the vast majority (90%) of new infections. UK scientists have said that the Delta variant is between 40% and 80% more transmissible than the previously-dominant Alpha variant, which was first identified in the UK (Kent).[111]
See also[edit]

Medicine portal
Viruses portal
SARS-CoV-2 Alpha variant
SARS-CoV-2 Beta variant
SARS-CoV-2 Gamma variant
SARS-CoV-2 Theta variant
SARS-CoV-2 Iota variant
SARS-CoV-2 Lambda variant
SARS-CoV-2 Kappa variant
Notes[edit]

^ Other names include:
– G/452R.V3[1]
– Indian variant
References[edit]

^ "COVID-19 Weekly Epidemiological Update (2 May 2021)" (PDF). reliefweb.int. World Health Organization. Retrieved 6 May 2021.
^ "Confirmed cases of COVID-19 variants identified in UK". www.gov.uk. 15 April 2021. Retrieved 20 April 2021. This article incorporates text published under the British Open Government Licence v3.0:
^ Jump up to:a b c d "Tracking of Variants". gisaid.org. GISAID. 26 April 2021. Retrieved 30 May2021.
^ Jump up to:a b c "Expert reaction to cases of variant B.1.617 (the 'Indian variant') being investigated in the UK". Science Media Centre. Retrieved 20 April 2021.
^ Jump up to:a b "Covid: WHO renames UK and other variants with Greek letters". BBC News. 31 May 2021. Retrieved 8 June 2021.
^ Jump up to:a b Shang, Jian; Yushun, Wan; Lou, Chuming; Ye, Gang; Geng, Qibin; Auerbach, Ashley; Fang, Li (2020). "Cell entry mechanisms of SARS-CoV-2". Proceedings of the National Academy of Sciences. 117 (21): 11727–11734. doi:10.1073/pnas.2003138117. PMC 7260975. PMID 32376634.
^ "expert reaction to VUI-21APR-02/B.1.617.2 being classified by PHE as a variant of concern". sciencemediacentre.org. 7 May 2021. Retrieved 18 June 2021.
^ Jump up to:a b c d Starr, Tyler N.; Greaney, Allison J.; Dingens, Adam S.; Bloom, Jesse D. (April 2021). "Complete map of SARS-CoV-2 RBD mutations that escape the monoclonal antibody LY-CoV555 and its cocktail with LY-CoV016". Cell Reports Medicine. 2 (4): 100255. doi:10.1016/j.xcrm.2021.100255. PMC 8020059. PMID 33842902.
^ "SARS-CoV-2 variants of concern and variants under investigation in England" (PDF). 27 May 2021. Retrieved 18 June 2021. This article incorporates text published under the British Open Government Licence v3.0:
^ "Confirmed cases of COVID-19 variants identified in UK". www.gov.uk. 7 May 2021. Archived from the original on 7 May 2021. Retrieved 7 May 2021. This article incorporates text published under the British Open Government Licence v3.0:
^ WHO labels a Covid strain in India as a ‘variant of concern’ — here’s what we know, CNBC, 11 May 2021.
^ WHO says India Covid variant of 'global concern', BBC News, 11 May 2021.
^ India’s second COVID-19 wave, The Wire Science, 22 April 2021.
^ "Genomic epidemiology of novel coronavirus - Global subsampling (Filtered to B.1.617)". nextstrain.org. Retrieved 5 May 2021.
^ "SARS-CoV-2 Variant Classifications and Definitions". cdc.gov. Centers for Disease Control and Prevention. 15 June 2021. Retrieved 18 June 2021.
^ Jump up to:a b "SARS-CoV-2 variants of concern as of 24 May 2021". European Centre for Disease Prevention and Control. Retrieved 29 May 2021.
^ "SARS-CoV-2 Variant Classifications and Definitions". CDC.gov. Centers for Disease Control and Prevention. Retrieved 15 June 2021.
^ Greenwood, Michael (30 March 2021). "SARS-CoV-2 mutation T478K spreading at alarming speed in Mexico". Medical News. Retrieved 15 June 2021.
^ Zhang, Wenjuan; Davis, Brian D.; Chen, Stephanie S.; Sincuir Martinez, Jorge M.; Plummer, Jasmine T.; Vail, Eric (6 April 2021). "Emergence of a Novel SARS-CoV-2 Variant in Southern California". JAMA. 325 (13): 1324–1326. doi:10.1001/jama.2021.1612. PMC 7879386. PMID 33571356.
^ Koshy, Jacob (8 April 2021). "Coronavirus | Indian 'double mutant' strain named B.1.617". The Hindu. Retrieved 19 April 2021. Though these mutations have individually been found in several other coronavirus variants, the presence of both these mutations together have been first found in some coronavirus genomes from India.
^ Jump up to:a b Haseltine, William. "An Indian SARS-CoV-2 Variant Lands In California. More Danger Ahead?". Forbes. Retrieved 20 April 2021.
^ Hoffmann, Markus; Hofmann-Winkler, Heike; Krüger, Nadine; Kempf, Amy; Nehlmeier, Inga; Graichen, Luise; Sidarovich, Anzhalika; Moldenhauer, Anna-Sophie; Winkler, Martin S.; Schulz, Sebastian; Jäck, Hans-Martin; Stankov, Metodi V.; Behrens, Georg M. N.; Pöhlmann, Stefan (2021). "SARS-CoV-2 variant B.1.617 is resistant to Bamlanivimab and evades antibodies induced by infection and vaccination". bioRxiv. Cold Spring Harbor Laboratory. doi:10.1101/2021.05.04.442663. Collectively, our study reveals that antibody evasion of B.1.617 may contribute to the rapid spread of this variant... ...The RBD of the B.1.617 S protein harbors two mutations associated with (L452R) or suspected (E484Q) of antibody evasion... ...Moreover, E484K present the B.1.351 and P.1 variants confers antibody resistance (Li et al., 2021) and one could speculate that exchange E484Q might have a similar effect.
^ "SARS-CoV-2 Variant Classifications and Definitions". Centers for Disease Control and Prevention. 12 May 2021. Retrieved 16 May 2021.
^ Di Giacomo, Simone; Mercatelli, Daniele; Rakhimov, Amir; Giorgi, Federico M. (2021). "Preliminary report on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Spike mutation T478K". Journal of Medical Virology. doi:10.1002/jmv.27062. PMID 33951211.
^ "Threat Assessment Brief: Emergence of SARS-CoV-2 B.1.617 variants in India and situation in the EU/EEA". European Centre for Disease Prevention and Control. 11 May 2021. Retrieved 17 May 2021.
^ Delta variant Covid symptoms ‘include headaches, sore throat and runny nose’ The Guardian
^ Headache and runny nose linked to Delta variant
^ The COVID-19 Delta Variant: Here's Everything You Need to Know
^ Yadav, PD; Sapkal, GN; Abraham, P; Ella, R; Deshpande, G; Patil, DY; Nyayanit, DA; Gupta, N; Sahay, RR; Shete, AM; Panda, S; Bhargava, B; Mohan, VK (7 May 2021). "Neutralization of variant under investigation B.1.617 with sera of BBV152 vaccinees". Clinical Infectious Diseases. doi:10.1093/cid/ciab411. PMID 33961693.
^ "Covishield Covaxin effective against 'Indian strain' of coronavirus study suggests". The Week. Retrieved 27 April 2021.
^ "Covaxin found to neutralise 617 variant of COVID-19, says Dr. Fauci". The Hindu. 28 April 2021.
^ "Covishield, Covaxin effective against 'Indian strain' of coronavirus, study suggests - ET HealthWorld". ETHealthworld.com. The Economic Times. 28 April 2021.
^ "WHO says India Covid variant of 'global concern'". BBC News. 11 May 2021. Retrieved 11 May 2021.
^ Ellyatt, Holly (24 May 2021). "Two doses of Covid vaccines provide effective protection against variant found in India: Study". CNBC.
^ Bernal, Jamie Lopez; Andrews, Nick; Gower, Charlotte; Gallagher, Eileen; Simmons, Ruth; Thelwall, Simon; Stowe, Julia; Tessier, Elise; Groves, Natalie; Dabrera, Gavin; Myers, Richard; Campbell, Colin; Amirthalingam, Gayatri; Edmunds, Matt; Zambon, Maria; Brown, Kevin; Hopkins, Susan; Chand, Meera; Ramsay, Mary (24 May 2021). "Effectiveness of COVID-19 vaccines against the B.1.617.2 variant". medRxiv. doi:10.1101/2021.05.22.21257658.
^ "Pfizer Vaccine Less Effective, Still Protects Against Variant Found In India: Study". NDTV.com. Retrieved 29 May 2021.
^ Planas, Delphine; Veyer, David; Baidaliuk, Artem; Staropoli, Isabelle; Guivel-Benhassine, Florence; Rajah, Maaran; Planchais, Cyril; Porrot, Francoise; Robillard, Nicolas; Puech, Julien; Prot, Matthieu; Gallais, Floriane; Gantner, Pierre; Velay, Aurelie; Le Guen, Julien; Kassis-Chikhani, Najibi; Edriss, Dhiaeddine; Belec, Laurent; Seve, Aymeric; Pere, Helene; Courtellemenont, Laura; Hocqueloux, Laurent; Fafi-Kremer, Samira; Prazuck, Thierry; Mouquet, Hugo; Bruel, Timothee; Simon-Loriere, Etienne; Rey, Felix; Schwartz, Olivier (27 May 2021). "Reduced sensitivity of infectious SARS-CoV-2 variant B.1.617.2 to monoclonal antibodies and sera from convalescent and vaccinated individuals". bioRxiv. doi:10.1101/2021.05.26.445838.
^ Wall, Emma C; Wu, Mary; Harvey, Ruth; Kelly, Gavin; Warchal, Scott; Sawyer, Chelsea; Daniels, Rodney; Hobson, Philip; Hatipoglu, Emine; Ngai, Yenting; Hussain, Saira; Nicod, Jerome; Goldstone, Robert; Ambrose, Karen; Hindmarsh, Steve; Beale, Rupert; Riddell, Andrew; Gamblin, Steve; Howell, Michael; Kassiotis, George; Libri, Vincenzo; Williams, Bryan; Swanton, Charles; Gandhi, Sonia; Bauer, David LV (June 2021). "Neutralising antibody activity against SARS-CoV-2 VOCs B.1.617.2 and B.1.351 by BNT162b2 vaccination". The Lancet. doi:10.1016/s0140-6736(21)01290-3. ISSN 0140-6736. PMC 8175044.
^ "COVID-19 vaccine: Pfizer jabs not the best for Delta variant, says Lancet study". The New Indian Express. 5 June 2021.
^ "UK study finds vaccines offer high protection against hospitalisation from Delta variant". Reuters. 14 June 2021. Retrieved 15 June 2021.
^ Deng, Xianding; Garcia-Knight, Miguel A.; Khalid, Mir M.; Servellita, Venice; Wang, Candace; Morris, Mary Kate; Sotomayor-González, Alicia; Glasner, Dustin R.; Reyes, Kevin R.; Gliwa, Amelia S.; Reddy, Nikitha P.; Martin, Claudia Sanchez San; Federman, Scot; Cheng, Jing; Balcerek, Joanna; Taylor, Jordan; Streithorst, Jessica A.; Miller, Steve; Sreekumar, Bharath; Chen, Pei-Yi; Schulze-Gahmen, Ursula; Taha, Taha Y.; Hayashi, Jennifer; Simoneau, Camille R.; Kumar, G. Renuka; McMahon, Sarah; Lidsky, Peter V.; Xiao, Yinghong; Hemarajata, Peera; Green, Nicole M.; Espinosa, Alex; Kath, Chantha; Haw, Monica; Bell, John; Hacker, Jill K.; Hanson, Carl; Wadford, Debra A.; Anaya, Carlos; Ferguson, Donna; Frankino, Phillip A.; Shivram, Haridha; Lareau, Liana F.; Wyman, Stacia K.; Ott, Melanie; Andino, Raul; Chiu, Charles Y. (20 April 2021). "Transmission, infectivity, and neutralization of a spike L452R SARS-CoV-2 variant". Cell. 0. doi:10.1016/j.cell.2021.04.025. ISSN 0092-8674. PMC 8057738. PMID 33991487. Retrieved 26 April 2021.
^ "Gupta Lab, Cambridge on Twitter". Twitter. ...likely vaccines will protect against severe illness and death but not against infection in those with poorer immune responses.
^ "Gupta Lab, Cambridge on Twitter". Twitter.
^ Doucleff, Michaeleen (24 April 2021). "People Are Talking About A 'Double Mutant' Variant In India. What Does That Mean?". NPR.org. NPR.
^ Dey, Sushmi. "Covid second wave in India: Percentage of young infected in second wave same, but more serious". The Times of India. Retrieved 27 April 2021.
^ "Weekly epidemiological update on COVID-19 - 11 May 2021". World Health Organization. 11 May 2021. Retrieved 12 May 2021.
^ "PANGO lineages Lineage B.1.617.2". cov-lineages.org. Retrieved 16 June 2021.
^ Jump up to:a b "PANGO lineages Lineage B.1.617". cov-lineages.org. Retrieved 26 May 2021.
^ "Tracking variants of the novel coronavirus in Canada". ctvnews.ca. 19 February 2021. Retrieved 10 June 2021.
^ "Fiji fears a coronavirus 'tsunami' after outbreak found to be Indian variant". SBS News. 28 April 2021. Retrieved 28 April 2021.
^ Soni, Parul (30 April 2021). "Israel Is The Most Vaccinated Country, But The B.1.617 Is Threatening It Now". International Business Times. IBT Media.
^ "Israel logs Indian COVID-19 variant, sees some vaccine efficacy against it". Reuters. 20 April 2021. Retrieved 24 April 2021.
^ "זוהו 41 מקרים של הזן (הווריאנט) ההודי, מתוכם 24 חוזרים מחו"ל" [41 cases of the Indian variety have been identified, of which 24 are from abroad]. GOV.IL (in Hebrew). Retrieved 29 April 2021.
^ "Minister zdrowia: mamy kolejne dwa ogniska związane z mutacją indyjską koronawirusa" [Health Minister: We have two more outbreaks related to the Indian mutation of the coronavirus]. tvn24.pl (in Polish). 4 May 2021. Retrieved 4 May 2021.
^ "Nepal reports more Covid-19 deaths and record daily new infections". Kathmandu Post. 11 May 2021. Retrieved 11 May 2021.
^ "Coronavirus live news, 16:54, 28 April 2021". The Guardian. 28 April 2021. Retrieved 28 April 2021.
^ Jump up to:a b "Indian Covid variant reaches Finland". YLE. Finland. 29 April 2021. Retrieved 13 May 2021.
^ "Intialaiseen muunnokseen on sairastunut Suomessa kymmenkunta henkeä – Uudenmaan koronaviruskanta on vaihtunut täysin alkuvuoden aikana" [Abotu a dozen people in Finland have contracted the Indian variant - the coronavirus variants seen in Uusimaa have completely changed in the first part of the year]. yle.fi (in Finnish). 10 May 2021. Retrieved 17 May 2021.
^ "Virologist: Indian variant not major concern in Finland, though care should be taken". Yle. Finland. 27 May 2021. Retrieved 27 May 2021.
^ "Russia records first cases of COVID variant found in India". The Economic Times. Retrieved 13 May 2021.
^ "IEDCR: Indian Covid variant found in six Bangladeshis". Dhaka Tribune. 17 May 2021. Retrieved 18 May 2021.
^ "যশোরে আরো ৩জনের শরীরে করোনার ভারতীয় ভ্যারিয়েন্ট শনাক্ত" [Indian variant of coronavirus identified in 3 more poeple in Jessore District]. Youtube. Jamuna TV. 18 May 2021. Retrieved 18 May 2021.
^ "Cases of South African and Indian coronavirus strains detected in Argentina". MercoPress. 11 May 2021. Retrieved 11 May 2021.
^ Yabiladi.com. "Morocco : Two cases of the Indian variant of Covid-19 confirmed in Casablanca". en.yabiladi.com (in French). Retrieved 3 May 2021.
^ "Indian variant of Covid-19 confirmed in Thailand". Bangkok Post. 10 May 2021. Retrieved 11 May 2021.
^ "Algeria finds first cases of Indian coronavirus variant". Reuters. 4 May 2021. Retrieved 14 May 2021.
^ "Botswana confirms new COVID-19 variant". Weekend Post. 17 May 2021. Retrieved 18 May 2021.
^ "Cyprus finds first cases of Indian COVID variant". Reuters. 19 May 2021. Retrieved 19 May 2021.
^ Jump up to:a b c "Nigeria, Algeria report Indian variant of the coronavirus, WHO says without further details". africanews.com. 13 May 2021. Retrieved 14 May 2021.
^ Jump up to:a b c "Weekly epidemiological update on COVID-19 - 18 May 2021". World Health Organization. 18 May 2021. Retrieved 19 May 2021.
^ "Iran reports three cases of Indian coronavirus variant". Al Arabiya. 5 May 2021. Retrieved 14 May 2021.
^ "Covid Indian Variant Detected In Kenya". ndtv.com. 5 May 2021. Retrieved 7 May2021.
^ "Indisk virusvariant påvist i Norge" [Indian virus variant detected in Norway]. dagbladet.no. 16 April 2021. Retrieved 28 April 2021.
^ "First case of Indian variant detected at Tocumen International". ndtv.com. 8 May 2021. Retrieved 14 May 2021.
^ "Update On Covid-19 (08th May 2021) - SA Corona Virus Online Portal". SA Corona Virus Online Portal. Retrieved 10 May 2021.
^ "Covid-19 Indian variant spreads to neighbouring countries; detected in Sri Lanka, Bangladesh". Times of India. 8 May 2021. Retrieved 11 May 2021.
^ "Raising fears of COVID surge, Uganda detects Indian variant, official says". Reuters. 30 April 2021. Retrieved 8 May 2021.
^ "Philippines detects 2 cases of COVID-19 India variant". Rappler. 11 May 2021. Retrieved 11 May 2021.
^ "Philippines detects 10 more cases of coronavirus variant first detected in India". Philippine Star. 15 May 2021. Retrieved 15 May 2021.
^ News, ABS-CBN (29 May 2021). "DOH logs new COVID-19 variant cases in PH; only 26 active". Retrieved 29 May 2021.
^ "Vietnam detects 'double mutant' Indian variant of coronavirus for 1st time". tuoitrenews.vn. 2 May 2021. Retrieved 17 May 2021.
^ "Indian coronavirus variant found in COVID-19 cases linked to National Hospital for Tropical Diseases". vietnamnews.vn. 11 May 2021. Retrieved 17 May 2021.
^ SP identifica primeiro caso de variante do coronavírus em passageiro vindo da Índia26/05/2021 g1.globo.com, accessed 26 May 2021
^ Covid-19: Maranhão registra primeiros casos da variante indiana 21 May 2021 pebmed.com.br, accessed 26 May 2021
^ Barbosa, Alex (24 May 2021). "Identificação da variante indiana do coronavírus coincide com aumento de internações no Maranhão". g1.globo.com (in Portuguese). TV Mirante e G1 MA.
^ Coronavírus: Primeiro caso da variante indiana é confirmado no Paraná, diz Sesa (tr. "Coronavirus: First case of the Indian variant is confirmed in Paraná, says Sesa ") 02/06/2021 g1.globo.com, accessed 3 June 2021
^ https://g1.globo.com/google/amp/go/goias/noticia/2021/06/18/variante-delta-do-coronavirus-e-identificada-e-tem-transmissao-comunitaria-em-goiania.ghtml
^ "Lithuania detects first case of coronavirus Delta variant from India". lrt.lt/en/news-in-english. 17 June 2021. Retrieved 17 June 2021.
^ "Gottlieb says Delta variant likely to become dominant U.S. strain". news.yahoo.com. Retrieved 15 June 2021.
^ "CDC covid variant tracker".
^ "RIVM Covid variant tracker".
^ "Merkel says Germany is in race to vaccinate against Delta variant".
^ SARS-CoV-2 variants of concern and variants under investigation in England - Technical briefing 10 (PDF) (Report). London. Public Health England. 7 May 2021. Retrieved 7 May 2021. This article incorporates text published under the British Open Government Licence v3.0:
^ "British scientists warn over Indian coronavirus variant". Reuters. 7 May 2021. Retrieved 7 May 2021.
^ Davis, Nicola (7 May 2021). "Indian Covid variant is 'of concern', says Public Health England". The Guardian. London. Retrieved 7 May 2021.
^ "Confirmed cases of COVID-19 variants identified in UK". www.gov.uk. 3 June 2021. Retrieved 3 June 2021. This article incorporates text published under the British Open Government Licence v3.0:
^ "Confirmed cases of COVID-19 variants identified in UK". www.gov.uk. 11 June 2021. Archived from the original on 11 June 2021. Retrieved 11 June 2021. This article incorporates text published under the British Open Government Licence v3.0:
^ Carrigg, David (21 April 2021). "COVID-19: Double mutant virus first identified in India is now in B.C." Vancouver Sun. Retrieved 28 April 2021.
^ Ritchie, Josh (22 April 2021). "First case of B.1.617 variant confirmed in Alberta". edmonton.citynews.ca.
^ "One Death, Eight New Cases of COVID-19, Delta Variant Cases Identified, State of Emergency Renewed". 11 June 2021. Retrieved 11 June 2021.
^ "Fiji fears a coronavirus 'tsunami' after outbreak found to be Indian variant". SBS News. 28 April 2021. Retrieved 28 April 2021.
^ "Philippines detects 2 cases of COVID-19 India variant". Rappler. 11 May 2021. Retrieved 11 May 2021.
^ Jump up to:a b Shakil, F.M. (18 May 2021). "Pakistan in blind denial over Indian virus variant". Asia Times. Retrieved 19 May 2021.
^ "Iraqi labs don't have ability to identify Indian Covid variant". Healthworld, Economic Times. 11 May 2021. Retrieved 19 May 2021.
^ report, Web. "India Covid crisis: 20 countries that have imposed travel bans, suspensions". Khaleej Times. Retrieved 1 May 2021.
^ "Countries enact travel bans to contain India's COVID variant—and protect against 'a global resurgence all over again'". Fortune. Retrieved 1 May 2021.
^ "Countries that have put India in red list due to rising COVID-19 cases". Times of India Travel. Retrieved 1 May 2021.
^ "Indian variant: Tower blocks quarantined in Germany". BBC News. Retrieved 19 May2021.
^ Choudhury, Saheli Roy (20 May 2021). "Singapore orders Facebook, Twitter to correct false claims on a 'new' Covid variant". CNBC. Retrieved 23 May 2021.
^ Jump up to:a b "Singapore says 'no truth' to Kejriwal's new variant claims". BBC News. 19 May 2021. Retrieved 23 May 2021.
^ "'Freedom Day' for England pushed back 4 weeks to July 19". AP News. 14 June 2021. Retrieved 15 June 2021.
External links[edit]
Public Health England: Variants of concern or under investigation, B.1.617

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