Currently circulating variants of interest (VOIs) as of 09 August 2023
Pango lineage Nextstrain clade Genetic features Earliest documented samples Date of designation and risk assessments
XBB.1.5 23A
Recombinant of BA.2.10.1 and BA.2.75 sublineages, i.e. BJ.1 and BM.1.1.1, with a breakpoint in S1.
XBB.1 + S:F486P (similar Spike genetic profile as XBB.1.9.1)
21-10-2022
11-01-2023
XBB.1.5 Rapid Risk Assessment, 11 January 2023
XBB.1.5 Updated Rapid Risk Assessment, 25 January 2023
XBB.1.5 Updated Risk Assessment, 24 February 2023
XBB.1.5 Updated Risk Assessment, 20 June 2023
XBB.1.16 23B
Recombinant of BA.2.10.1 and BA.2.75 sublineages, i.e. BJ.1 and BM.1.1.1
XBB.1 + S:E180V, S:K478R and S:F486P 09-01-2023
17-04-2023
XBB.1.16 Initial Risk Assessment, 17 April 2023
XBB.1.16 Updated Risk Assessment, 05 June 2023
EG.5 Not assigned
XBB.1.9.2 + S:F456L
Includes EG.5.1: EG.5 + S:Q52H
17-02-2023
09-08-2023
EG.5 Initial Risk Evaluation, 09 August 2023
Currently circulating variants under monitoring (VUMs) (as of 09 August 2023)
Pango lineage Nextstrain clade Genetic features Earliest documented samples Date of designation and risk assessments
BA.2.75 22D BA.2 + S:K147E, S:W152R, S:F157L, S:I210V, S:G257S, S:D339H, S:G446S, S:N460K, S:Q493R reversion 31-12-2021 06-07-2022
CH.1.1 22D BA.2.75 + S:L452R, S:F486S 27-07-2022 08-02-2023
XBB* 22F BA.2+ S:V83A, S:Y144-, S:H146Q, S:Q183E, S:V213E, S:G252V, S:G339H, S:R346T, S:L368I, S:V445P, S:G446S, S:N460K, S:F486S, S:F490S 19-08-2022 12-10-2022
XBB.1.9.1 Not assigned
Recombinant of BA.2.10.1 and BA.2.75 sublineages, i.e. BJ.1 and BM.1.1.1
XBB.1 + S:F486P (similar Spike genetic profile as XBB.1.5)
05-12-2022 30-03-2023
XBB.1.9.2# Not assigned
Recombinant of BA.2.10.1 and BA.2.75 sublineages, i.e. BJ.1 and BM.1.1.1
XBB.1 + S:F486P, S:Q613H
05-12-2022 26-04-2023
XBB.2.3 Not assigned
Recombinant of BA.2.10.1 and BA.2.75 sublineages, i.e. BJ.1 and BM.1.1.1
XBB + S:D253G, S:F486P, S:P521S
09-12-2022 17-05-2023
* Excludes XBB sublineages listed here as VOIs and VUMs
# Excludes XBB.1.9.2 sublineages listed here as VOIs and VUMs
